• Lisa Tuccio

The Power of the Nrf2 Pathway



For Starters, what is Nrf2?


The Nrf2 is a powerful protein and is referred to as the “master regulatory of antioxidant, detoxification and cell defense gene expression...” and just for these reasons, there has been so much research trying to explore how activating this life-sustaining pathway may have critical importance for applications for our health and longevity. The Nrf2 pathway has been in studies involving various brain degenerative disorders including Alzheimer’s disease, Parkinson’s disease, Multiple Sclerosis, and Autism.


What can the Nrf2 Do for You?


When the body is young and healthy it is able to take care of the balance between cellular damage, repair and rejuvenation. The Nrf2 pathway is one way the body is signaled to take care of repairing damage. As some call it, “The guardian of the lifespan” because the ability to protect your health as you age. This doesn’t mean you have to be young to have a working Nrf2 pathway, for as long as your alive the pathway will be present, it’s all about the matter of activating the Nrf2 pathway.


Should the Nrf2 Matter?


Every little thing in our body should matter, sometimes some areas more than others but, according to science, and Neurologist Dr. David Perlmutter, everyone suffers from different levels of stress. Some stress is good for you, but too much of it can lead to it being a bad thing. So, here’s where the Nrf2 becomes Important: Nrf2 responds to the rising stress levels by directing the cell to start making hundreds of unique protective molecules that work to bring stress levels back it’s normal state.


How to activate the Nrf2 Pathway


For something that is so complex to explain in scientific terms, activating the pathway is simple. It’s all about what you eat: Blueberries, grapes, avocado, spinach, tomatoes, sweet potatoes, apples, onions and broccoli are great foods to increase the activity of the Nrf2. The foods listed, all contain a heavy number of antioxidants and vitamins that you need in order to boost the activation. Other compounds like, turmeric, green tea leaf, black pepper and pine bark, can also help boost your Nrf2 levels.

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